I'm in the same boat. Running Twonky Server 8.2.1 on my QNAP TS-251 (firmware up to date). Twonky finished scanning everything.
Whenever I click on an album or song to play in my browser (Chrome, also up to date), I get the error: "Can not beam to device. Try to open the media content in a new browser window using another player." If I click OK, it opens up a new tab trying to play the file, but it tries to access the file from the localhost (http://127.0.0.1:9000/..
.) instead of the QNAP's IP. If I change the IP to the QNAP's public/static IP, I can play the file directly, but not through the Twonky interface, just through Chrome's audio file player.
I know Twonky is working somewhat correctly though because I can access it through 8player on my iPhone. Any ideas what's going on? Is it maybe something with the browser/browser interface?